[abstract] ISOLATION AND IDENTIFICATION -MANGOSTIN AS A MARKER COMPOUND FROM Garcinia mangostana L. HULL

By: Yarni L1, Nasrullah I1, Murhandini S1and Rahayu WP1,2

1Research Center for Drug and Food, National Agency for Drug and Food Control
2Department of Food Science and Technology, Bogor Agricultural University

Garcinia mangostana L. hull is empirically used as a traditional medicinefor diarrhea, sprue and antipyretic. Chemical constituens of Garcinia mangostana L. hull are xanthon compounds such as mangostin, 8-deoxygartanin, gartanin, mangostinone, tovophylin A and cudraxanthone. Chemical examination of ethyl acetate fraction began with the isolation of a-mangostin then its structure elucidation was carried out based on spectroscopic evidence by using UV-Vis spectrophotometer, FT-IR, 1H-NMR and 13C-NMR. This a-mangostin will be used as marker to control the quality of traditional medicine products which contain Garcinia mangostana L. hull powder or extract.

Keywords:Garcinia mangostana L. hull, xanthon compounds, a-mangostin, marker compound

Presented at 38th Meeting of National Working Group for Indonesian Medical Plant International Conference on Medicinal Plants, Surabaya-Indonesia, July 21-23th 2010.

 

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